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Clinical pharmacokinetics and pharmacodynamics : concepts and applications
Malcolm Rowland, Thomas N. Tozer.
Veterinary Medicine Library Call Number
  Veterinary Medicine Library Course Reserve RM301.5 .R68 2011 (Browse Shelf) Available - On Reserve (what's this?)
Other Titles
Other Authors
  • ISBN: 9780781750097
  • ISBN: 0781750091
  • OCLC Number: 426115435
  • Includes index.
  • Rev. ed. of: Clinical pharmacokinetics. 1995.
Table of Contents

Therapeutic relevance -- Fundamental concepts and terminology -- Kinetics following an intravenous bolus dose -- Membranes and distribution -- Elimination -- Kinetics following an extravascular dose -- Absorption -- Response following a single dose -- Therapeutic window -- Constant-rate input -- Multiple-dose regimens -- Variability -- Genetics -- Age, weight, and gender -- Disease -- Nonlinearities -- Drug interactions -- Initiating and managing therapy -- Distribution kinetics -- Metabolites and drug response -- Protein drugs -- Prediction and refinement of human kinetics from in vitro, preclinical, and early clinical data.